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KMID : 0388220130200030190
Journal of the Korean Rheumatism Association
2013 Volume.20 No. 3 p.190 ~ p.193
A Case of Sweet¡¯s Syndrome Associated with Rheumatoid Arthritis Involving Multiple Skin Lesions
Seo Young-Ho

Lee Young-Ho
Ji Jong-Dae
Song Gwan-Gyu
Yoo Seu-Hee
Ahn Jem-Ma
Choi Seong-Jae
Abstract
Sweet¡¯s syndrome is a neutrophilic dermatoses characterized by the abrupt onset of fever, leukocytosis and skin lesions that are infiltrated by neutrophils. Most skin lesions are in the form of erythematous tender papules or nodules, usually affecting the upper limbs, face or neck and histologically a dense perivascular infiltrate of neutrophils without vasculitis. Sweet¡¯s syndrome can be associated with several disorders, such as inflammatory bowel disease, malignant tumors, and autoimmune diseases including rheumatoid arthritis. We report a case of Sweet¡¯s syndrome with associated rheumatoid arthritis. The patient had multiple skin lesions in her face, neck, both upper and lower extremities except trunk, and complained fever, chills and arthralgia. The result of skin biopsy showed mature neutriphil infiltration and leukocytoclasia of dermis without vasculitis, which was compatible with Sweet¡¯s syndrome.
KEYWORD
Sweet¡¯s syndrome, Rheumatoid arthritis
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